Innovative Techniques to Synthesize Breakthrough Molecules

Case Studies for Optimizing Organic Chemistry R&D

Today, researchers apply effective methods to expand research and development of innovative molecules and optimized process conditions. This white paper discusses how scientists open new possibilities for control, optimization, and reporting of critical process conditions.

Four case studies highlight how leading pharmaceutical companies impact synthesis lab performance:

  • Identifying the ideal operating conditions for a successful triflation reaction
  • Parameter control to avoid impurity formation during a guanidine reaction
  • Central composite Design of Experiment (DoE) for guanidine reaction scale-up
  • Inline reaction rate meter tracking a two-step lithium borohydride reduction