How to Measure pH in Small Volume Samples

Discover the Benefits of Using Specialized pH Sensors

Scientists may find themselves working with small samples in situations where, for example, the material is harmful, expensive or only available in limited quantities. Obtaining accurate results first time is critical, as it may not be possible to repeat the analysis. The use of a pH microsensor helps to minimize the need for sample manipulation, a known source of measurement errors.

Measuring the pH of small volume samples is often necessary in life sciences research. These samples typically represent costly experiments, and sample manipulation can introduce measurement errors. With the right pH sensor and measurement technique, it is possible to minimize sample manipulation to achieve accurate results.

This application note explores the challenges associated with the measuring the pH of small samples and provides guidelines for measuring procedures and sensor selection, including:

  • Measuring the pH of small volume samples
  • Measuring the pH with surface sensors
  • Using surface pH sensors to prevent sample contamination
  • Measuring sample temperature
Following these guidelines can help you to successfully overcome the challenges of small volume measurements and achieve accurate, repeatable results.